Production of transgenic animals notes

Let us discuss a few of them here. A transgenic animal is an animal in which one or more genes have been introduced into its nonreproductive cells. After injecting the dna the embryo is implanted into the uterus of receptive females. Transgenic animals can be used to produce valuable products. Transgenic animals can be created by manipulating embryonic stem cells. Transgenic mice are developed by injecting dna into the oocytes or 1 2 celled embryos taken from female mice. The transgenic animals are created because of the benefits they provide to the man. Theoretically all living beings can be genetically manipulated. The major successes have been achieved in the transfer of. Animals with manipulated genetic material carrying recombinant dna are known as transgenic animals. Transgenic animals are those that have been genetically modified. Transgene is incorporated into the es cell by microinjection by a retro virus by electroporation transgenic stem cells are grown in vitro. Following natural gestation and birth offspring are subject to tissue biopsy and blood sampling. The production of transgenic animals has focused mainly on producing models e g the mouse for basic and medical research. Then they are inserted into a blastocyst and implanted into a host s uterus to grow normally.

Transgenic animals for the production of therapeutic and diagnostic proteins are produced by transferring fertilized transgene carrying embryos to recipient animals. Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Usually ear tissue and blood are screened by polymerase chain reaction and or southern analysis for the presence of the transgene. Production of transgenic animals notes. The first transgenic animal was produced in 1983 when genes for human growth hormone were introduced into mice. Applications of transgenic animals. There have been numerous reports and applications of transgenic plants in agriculture mainly to benefit the producer. The transgenic animals are created because of the benefits they provide to the man. Transgenic animals transgenic animals are animals that have been cloned. Es cells are obtained from the inner cell mass of a blastocyst. Transgenic animals are just one in a series of developments in the area of biotechnology.

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